Carrying a 4-1 advantage from the Camp Nou into Rome, Barcelona fans may not have been too anxious about any possible elimination from the elite competition from the quarterfinals.
Valverde was likewise harangued due to his failure to answer Roma's dominance as soon as they took an early lead during Edin Dzeko, before Daniele de Rossi's punishment and also a late Kostas Manolas suggestion sent the Italians as a result of on away goals. Real Madrid were the first when they defeated Barca 3-1 in the Spanish Super Cup back in August.
The 2014/15 campaign was the last time Barcelona and Messi lifted the coveted title, but in their three knockouts in the previous years (2-1 loss against Atletico, 7-0 drubbing by Bayern Munich and 3-2 defeat to Chelsea), Messi was not to be found on the scoresheet.
Luis Suarez and Lionel Messi of Barcelona arrive before the UEFA Champions League Quarter Final Leg Two match between AS Roma and FC Barcelona at Stadio Olimpico on April 10, 2018 in Rome, Italy. "We had high hopes this season and it has escaped us again", Iniesta said.
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That was the highest finish for the most active contract since December 1, 2014, according to FactSet. Prices of both crude benchmarks have risen more than 5 percent in the past two trading days.
"Barcelona got their backsides' handed to them last night - that's what happened", he told Ger.
The 33-year-old, who has been with Barca for 20 years, was asked if it could be his last Champions League appearance as a Barca player and replied, "it's a possibility, but we are all very upset today".
The team's other players couldn't do enough help Barcelona advance then, and this time Messi had even less support.
'It was a very big disappointment for the season we have had so far'.
The defeat means that Real Madrid are now the favourites to win the competition which will come as a crushing blow to the Argentinian as it would put rival Cristiano Ronaldo in a great position to overtake him as the record Ballon d'Or victor.