Foreign media reported over the weekend that Israeli forces attacked an Iranian military base in Syria.
Earlier in the day, pro-government media outlets had said the air defences were triggered by a missile attack, while people in the capital heard explosions in different areas.
Two missiles were intercepted in response.
A military site near Damascus came under attack just after midnight Saturday by missiles from the Israeli military, according to the Syrian state-run SANA news agency and the UK-based Syrian Observatory for Human Rights (SOHR). However, reports from Lebanon's Al-Mustaqbal TV and the Saudi-owned Al-Arabiya network stated that information on the deaths emerged from accounts on the Telegram messaging application linked to Iran's Revolutionary Guard Corps.
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The Israeli entity is closely linked to the terrorist organizations in Syria.
Prime Minister Benjamin Netanyahu has warned about Iran's plan to establish a permanent military presence in Syria, and said that "Israel will not let that happen". Israel has long justified its attacks inside Syria by claiming to be acting against Hezbollah and Iranian facilities and arms depots.
The Syrian conflict began in March 2011 against the Assad government, but it morphed into a civil war that has killed hundreds of thousands of people. Sky News said the strike had been conducted with air-to-surface missiles from Lebanese airspace.
In September, Israeli warplanes hit a military position near the Mediterranean coast in western Syria, killing two soldiers and causing material damage.